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Before we jump into treatment options, let's make sure we're all on the same page about what makes triple-negative breast cancer unique, especially when it has spread. **Triple-negative breast cancer** accounts for about 10-15% of all breast cancer cases. Its 'triple-negative' status means that it doesn't respond to hormonal therapies or drugs that target HER2, which are effective for other types of breast cancer. This lack of targeted receptors makes it more difficult to treat. When TNBC metastasizes, it most commonly spreads to the lungs, liver, brain, and bones. The prognosis for metastatic TNBC is generally poorer than for other subtypes of metastatic breast cancer, making it crucial to understand and optimize treatment strategies.
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