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La **razón principal para usar AIVD en lugar de ABVD** es generalmente para reducir o evitar la toxicidad pulmonar asociada con la bleomicina, que es un efecto secundario potencialmente grave y, en algunos casos, irreversible. La **toxicidad pulmonar inducida por bleomicina** puede manifestarse como tos, dificultad para respirar y, en casos severos, fibrosis pulmonar. karate1 youth league porec 2025 Si un paciente tiene un riesgo alto de toxicidad pulmonar, como aquellos con enfermedad pulmonar preexistente o una mayor edad, el médico podría optar por AIVD como una opción más segura. Además, **AIVD puede ser considerado en casos de resistencia o recurrencia del linfoma**, especialmente si el paciente ya ha recibido tratamiento con bleomicina.
