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Now, let's talk about how this all works on a cellular level. ER and PR are receptors that respond to the hormones estrogen and progesterone, respectively. These hormones can stimulate the growth of breast cancer cells. HER2, on the other hand, is a protein that promotes cell growth and division. When HER2 is overexpressed (meaning there are too many HER2 proteins), it can lead to aggressive cancer how to scan document from hp smart growth. In triple-positive breast cancer, all three of these mechanisms are active, which means the cancer has multiple pathways for growth. This is why a combined approach to treatment, targeting each of these pathways, is often the most effective. Hormone therapy tackles the ER and PR receptors, while anti-HER2 therapies target the HER2 protein. The combination often results in better control of the cancer and improved patient outcomes.
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